Endocrine Abstracts

Introduction: Graves orbitopathy (GO) is an inflammatory condition of the orbital fat and muscles and affect 30-50% of patients with Graves’ disease. The first-line treatment of moderate to severe GO according to EUGOGO is intravenous glucocorticoids, but 20-30% of the cases appear to be corticosteroid resistant or refractory. Promising results have been described with Tocilizumab (TCZ) as a second-line moderate to severe GO treatment.Case presentat...

Introduction: Graves’ Orbitopathy (GO), the most common extrathyroidal manifestation of Graves’ disease (GD), usually presents bilateral disease. However, a minority of patients present with unilateral disease, the prevalence of which is between 4,5% and 14%. The aim of our study is to evaluate the specific demographic and clinical characteristics and potential differences between bilateral and unilateral GO, and the association with disease activity and severity.</p...

Introduction: Latent autoimmune diabetes of the adults (LADA) is a heterogeneous type of diabetes sharing clinical characteristics of type 2 DM and serum markers of pancreatic autoimmunity detected in type 1 DM. It accounts for 2-12% of all patients with diabetes. The aim of our study is to identify the association between LADA and other systemic or organ-specific autoimmune diseases.Materials and Methods: We conducted an observational study in the outpa...